课程简介           详细

Spectrum elucidation course is one of required professional basic courses in the major of pharmacy, pharmaceutics, pharmaceutical engineering, chemistry, environmental protection, and food science. The predecessor of this course is the analysis of the industry in Hebei Institute of Chemical Technology, which was set up in 1975. Through the adjustment and merger of several colleges, this course has obtained the considerable development until now. Over the years of hard efforts, many effective works have been finished, including the design of teaching documents, the reform of teaching methods, the update of teaching media, bilingual education, the training of teachers, and the planning and construction of the laboratory. One of the outstanding teaching team has been formed with perfect practical ability, with structure of knowledge, education, title, age. The team is more reasonable, stable, and united.

From 2002, Hebei University of Science and Technology has began to conduct a comprehensive re-building in spectrum elucidation course and attempted to practise bilingual education. The original English teaching textbook has been adopted from that time. The curriculum compendium was revised and improved step by step. The new curriculum compendium increased the content of experiments based on keeping the original theory. The high-quality teaching has been fulfilled without changing the instruction hours. The teachers exploited multimedia courseware positively, and brought into full play the unique advantages of the teaching courseware, and realized teaching students in accordance of their aptitude. Related softwares were placed in an open laboratory, and students can take full advantage of the extra-curricular science and technology activities.

From 1975 to date, teachers obtained the rich practical teaching experiences, closely tracking the forefront of academic, which added the forefront and the new cross-subject knowledge into the course. For example, new two-dimensional NMR and Fourier transform data were added into teaching content. By so many improvements, the students can prompt understanding discipline front tendency. All of this new knowledge stimulates the study enthusiasm of the students. For the developing the soul of the course continually, the course team compiled courseware of spectral elucidation positively, instrumental analysis-related courses and textbooks, CAI multimedia courseware development. Instrumental analysis CAI multimedia courseware was published by Industry Press officially. At present, courseware has been used on internet perfectly.

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主持人介绍           详细

姚军

姚军,博士,教授。1997年获得The University of Illinois at Chicago博士学位,后作为研究员任职于美国辉瑞公司,合成化学公司等。2002年回国,在河北科技大学化学与制药工程学院从事教学和科研工作,为药物化学专业学术带头人。

研究方向:

新药开发,药物中间体工艺研究,不对称合成

教学工作经历

1.英语教学及双语教学。课程包括:波谱解析,药物化学,专业英语。

2.讲授本科生和研究生课程。课程包括:药物化学,天然药物化学,波谱解析,专业英语等。

3.主讲的《波谱解析》课程获得“2009年度河北科技大学校级精品课程”。另外,主讲的《波谱解析》课程曾经获得“2005年度河北省省级精品课程”和“河北科技大学校级精品课程”。

纵向科研课题 (2003年以来)

1.2009年河北省科技厅课题:“国家一类创新药物手性富马酸比索洛尔的制备”,课题编号:09276410D,主持人。

2.2006年河北省科技厅课题:“4-溴-N,N-二甲基苯胺生产新工艺”。项目编号:06215616,主持人。

3.2005年国家教育部项目:“桦木酸衍生物的制备”。教外司留[2005]383号,主持人。

4.2004年国家人事部项目:“药物控制释放材料聚酸酐的合成及其制剂研究”。国人部发[2004]99号,主持人。

5.2004年石家庄市科技局项目:“桂利嗪口腔崩解片的研究”。课题编号:2004423,主研人。

6.2004年国家自然科学基金项目:“抗肿瘤先导化合物Sansalvamide A 环肽及其相关物的设计合成”,项目批准号:30472074,主研人。

横向科研课题

2003年以来共计12项,合计科研经费200余万元。

例如:北京紫竹药业有限公司:“左炔诺孕酮杂质的合成及结构鉴定”,主持人,研究经费28万元。

科研成果

1.河北省科技厅课题“4-溴-N,N-二甲基苯胺生产新工艺”,国内领先水平。证书编号:20072269-1,主持人

2.河北省科技厅课题“桦木醇的提取和桦木酸的制备工艺研究”,国内领先水平,证书编号:20060118-1,主持人

3.河北省教育厅科学研究计划项目:“定向药物控制释放材料聚酸酐合成及缓释药物制剂的研究”,国际先进水平。证书编号:20060119-1,主持人

专利

共计申请21项国家发明专利。

例如:“手性芳氧丙醇胺类化合物及其盐的合成方法”,专利申请号200810055473.6(公开号:CN101323580A)。

发表文章

在Biochemistry等杂志发表论文共计26篇。

如:Mock, William; Yao, Jun; "Kinetic Characterization of the Serralysins: A Divergent Catalytic Mechanism Pertaining to Astacin-type Metalloproteases", Biochemistry 1997, 36: 4949-4958

其它荣誉

1.河北省高级评审委员会评委

2.河北省履行“禁止化学武器公约”技术专家

3.石家庄市反恐专家